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SALMOVAC 440 Alerta

Un producto de IDT BIOLOGIKA

IDT BIOLOGIKA - SALMOVAC 440 Precio y disponibilidad
Freeze-dried live Salmonella Enteritidis vaccine for oral use in chickens.
Qualitative and quantitative composition
A single dose of vaccine (1 ml reconstituted vaccine) contains not less than 1 x 108 colony-forming units of a genetically-stabile, double-attenuated (adenine-histidine auxotrophic) S. Enteritidis mutant.
Pharmaceutical form
Freeze-dried live vaccine, for oral administration via drinkers after reconstitution with drinking water.
Immunological properties
Oral vaccination of chickens results in epidemiologically relevant reduction in the level of shedding and persistence of Salmonella Enteritidis and Salmonella Typhimurium organisms.
Horizontal and vertical chains of infection are prevented or very substantially reduced in scope in flocks where high numbers of salmonella organisms are present.
Onset of immunity: 6 days after vaccination. Duration of immunity after single oral vaccination has been demonstrated up to 7 weeks after the vaccination.
Vaccination against Salmonella Enteritidis:
Efficacy was demonstrated in field studies of layers up to week 74 after hatching following 2x oral immunization.
Using an oral challenge model, with a challenge dose corresponding to a high number of salmonella organisms, the efficacy of the vaccine was demonstrated up to day 257 in birds vaccinated twice. The efficacy was assessed on the basis of the number of organisms in the liver and caeca and was statistically significant. Partial protection was found to continue up to week 79 (day 554) after hatching – with significantly lower numbers of salmonella organisms in the liver or caecum.
Vaccination against Salmonella Typhimurium:
Using an oral challenge mode birds vaccinated 3x were found to be protected against Salmonella Typhimurium up to week 73 after hatching.
Use of the vaccine does not affect serological testing against Salmonella Gallinarum (rapid serum agglutination test).
The attenuated vaccine strain can be distinguished from wild type Salmonella Enteritidis strains using the IDT Salmonella Diagnostic Kit.
ATC vet code: QI 01 AE 01
Target species

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IDT Biologika is an innovative privately-held company with more than 90 years of experience in research, development, manufacture and distribution of biologics for the global protection of human and animal health. With the expertise and capacity to handle large-scale campaign production of human vaccines and biopharmaceuticals, IDT Biologika brings development, testing and regulatory excellence along with state-of-the-art manufacturing lines required to advance projects with the highest level of quality, efficiency and consistency of supply.

Recognized for its technically sophisticated development, manufacture and handling of biopharmaceuticals and lyophilized compounds in EMA- and FDA-inspected facilities, IDT Biologika has developed into one of the world's leading pharmaceutical and biotechnological companies with a focus on three core areas: animal health, vaccines and pharmaceuticals. In 2015, IDT Biologika achieved sales of approximately €172 million, employing 1,250 employees.


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